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The mixture of testosterone is subject to the effects of the enzyme aromatase in the body, among the side effects of T-400 are side effects of estrogen. The rate of aromatization is directly related to the amount of used substance, and together with increasing doses aromatization is higher. Estrogenic side effects include: excessive water retention and bloating, elevated blood pressure (. due to water retention in the body), accelerated fat deposition and gynecomastia. The side effects of estrogen can be reduced or completely avoided by using aromatase inhibitors or SERMs (selective estrogen receptor modulators. Among androgenic side effects are: increased secretion of sebum (oily skin), acne (in terms of increased secretion of sebum), body hair growth, and increased risk of inducing male pattern baldness (MPB) in persons with a genetic predisposition. Anabolic / androgenic steroids can have deleterious effects on blood cholesterol levels. This includes a tendency to reduce HDL (good) cholesterol and increase LDL (bad) cholesterol. All anabolic steroids have the ability to suppress or shut down the natural endogenous production of testosterone in the body, and T-400 is no exception. After the end of the cycle, it is highly recommended to use a suitable PCT (Post Cycle Therapy).