Of the 1,000 or more Space Marine Chapters thought to be in existence at the present time, a blessed few can trace their beginnings back to an age more than ten thousand standard years ago in the late 30th Millennium, when the blessed Emperor of Mankind still walked amongst mortals. In those days, the Emperor first created the Primarchs , 20 immortal superhumans blessed with extraordinary intelligence, charisma and sheer physical might who were to be his generals and closest comrades during the Great Crusade to reunite the scattered and long-isolated human colony worlds after the end of the Age of Strife . The Primarchs wielded powers the like of which are not known in the Imperium today, yet they were lost to the Warp in an accident deep within the Emperor's gene-laboratories beneath the fortress that would become the Imperial Palace and were scattered, still in their gestation capsules, to worlds across the galaxy by the will of the Dark Gods of Chaos . The first Space Marines of the nascent Imperium were also the creation of that era, each made using the genetic inheritance of one of the Primarchs, albeit diluted a hundred times, for no merely human body could contain such power. As each of the Primarchs were encountered in turn by Imperial Expeditionary Fleets during the progress of the Great Crusade, they became the natural and obvious leader of the Space Marine Legion created from their genetic material and with whom they had so much in common. In many cases the Primarch's adopted world became the new base of operations for their Legion and was known henceforth as that Legion's homeworld. The Primarchs then recruited their loyal followers from each of these world's peoples into the ranks of their Legion while others were given rights to draw fresh blood from suitable warlike worlds that were liberated as the Great Crusade progressed.
Imbalance can cause illness. For example, Mitzi is a red Chow Chow who grew up in Portland, Maine. She enjoyed cold winters, lots of snow, fresh fish from the boat, and very few trips to the veterinarian. She felt well and expressed her health with exuberance and joy for life. She told everyone about her games and invited everyone to join in whether they wished it or not (Chow in your lap!) When Mitzi’s mom experience a job transfer to Florida, everyone was excited about boating in warmer waters, diving in the Florida Keys and gently swaying palm tree sunset breezes. One week Mitzi broke out with a painful, frantically itchy red oozing crusted sore on the right side of her hip. What happened?