Omeprazole acts as an inhibitor of CYP2C19. Omeprazole, given in doses of 40 mg daily for one week to 20 healthy subjects in cross-over study, increased Cmax and AUC of cilostazol by 18% and 26% respectively. C max and AUC of one of its active metabolites, 3,4-dihydro-cilostazol, which has 4-7 times the activity of cilostazol, were increased by 29% and 69% respectively. Co-administration of cilostazol with omeprazole is expected to increase concentrations of cilostazol and its above mentioned active metabolite. Therefore a dose reduction of cilostazol from 100 mg twice daily to 50 mg twice daily should be considered.
I was improperly catherized after the birth of my ²nd child causing a stricture in the uretha. After many uti’s and having surgical corrections the uti’s are infrequent. I believe this condition is my Achilles heel as bacteria will always be present in my urine. My bladder is scarred from having so many uti’s. I am on high dosage of vit C 50 000 and began uti like symptoms after being free of uti’s for a few years. Just began NOW D-mannose therapy so hoping for good results instead of a doctor visit and dreaded antibiotic.
Hello I hear this a lot about people saying magnesium gives them stomach distress there different types of magnesium 95% of the magnesium out there does go straight out your bowels the one magnesium that you need to get is called magnesium GLYniate doctors best Has a great magnesium GLY that is 100% absorbable And the beauty of it it gets into your cells which is where it’s needed instead of out through the toilet when it’s not wanted. We learned this from a natural path my daughter take 600 mg before bed I take 800 mg before bed it does not give us any diarrhea whatsoever in fact it has helped her migraines and my fibromyalgia immensely